Effect on liver includes its functioning, cells and tissue structure. Hepatoprotective activity of aqueous and ethanolic bixa orellana l. Phytochemical screening and evaluation of hepatoprotective activity of mimusops elengi linn. We wanted to evaluate the hepatoprotective activity of ocimum sanctum and observe whether synergistic. The rats were divided into four groups, each group consisting of six animals. It is involved with almost all the biochemical pathways to growth. The authors declare that there are no conflicts of interest.
The root bark of illicium henryi has been used in traditional chinese medicine to treat lumbar muscle strain and rheumatic pain. This is the first report of the hepatoprotective activity of the plant. Group one was kept on normal diet and served as control, the second. The present study was conducted to evaluate the hepatoprotective activity of a lcoholic extract of flowers dalbergia lanata against paracetamol induced liver damage in rats. It is used folklorically for the treatment of liver diseases, hypertension, malaria and cancer. Srinivasa rao, mohammed fazil ahmed and mohammed ibrahim.
The degree of protection was measured by estimating biochemical parameters such as serum glutamate oxaloacetate transaminase sgot, serum glutamate pyruvate transaminase sgpt,totalprotein tp, totalalbumin ta, alkaline. The effects of fipronil fpn on the liver of rats were studied. There is a lack of reliable hepatoprotective drugs in modern medicine to prevent and treat druginduced liver damage. Prabhakaran v, srinivas ashok kumar b, sheshadri shekar d, nandeesh r, subramanyam p and ranganayakulu d. The study was designed to evaluate the hepatoprotective activity of p. Meav was screened for hepatoprotective activity in pcm 3 gkg induced hepatotoxicity in wistar rats for 15 days at dose of. Study of the hepatoprotective activity of methanolic extract. Histopathologic examination assured the hepatoprotective activity of the extracts. Hepatic diseases are a major worldwide health problem, with frequently found in developing countries. Sitha institute of pharmaceutical sciences 2, hyderabad, andhra pradesh, india. Hepatoprotective hemiterpene glycosides from the rhizome. Iv hepatoprotective activity of date palm phoenix dactylifera pollen grains in rats by itimad abuowf ahmed abuowf b. In addition, hepatospecific serum markers will be disturbed. Shristi badhani, shivani sharma, amrita kainth, bharat parashar department of pharmacy, manav bharti university, solan, h.
Hepatoprotective and choleretic activity of tanacetum. The present study reports the investigation done on the hepatoprotective activity of ethanolic extract of mikania scandens l. Liver sections of the rats treated with methanolic extract of c. Bacteria associated with the red sea sponge amphimedon ochracea in ccl 4 induced hepatotoxicty in rats. In vitro and in vivo hepatoprotective activity of extracts of aerial parts.
The hepatoprotective activity of eeih might be attributed to the flavonoid compounds such as catechin 1, 3. Albino rats of either sex were divided into nine groups and treated for 7 days. Study of the hepatoprotective activity of methanolic. Hepatoprotective effects of triterpenoids from ganoderma. Hepatoprotective activity of date palm phoenix dactylifera pollen grains in rats by itimad abuowf ahmed abuowf b. Hepatoprotective activity of cassia fistula leaf extract. Liver as a target for oligonucleotide therapeutics. Hence, it was proposed to carry out a preliminary in vitro analysis of the hepato protective activity of the plant, which gave promising results. Hepatoprotective herbs are those herbs which are used to cure or prevent liver damage. Recent experience has shown that plant drugs are nontoxic, safe and even free from side effects 4. Srinivasa rao, mohammed fazil ahmed and mohammed ibrahim abstract the aim of the study is to investigate the hepatoprotective activity of melia azedarach leaves extracts against simvastatin induced hepatotoxicity. Image denoising is an important preprocessing task which is used before further processing of image. Hepatoprotective plants contain a variety of chemical constituents like phenols, coumarins, lignans, essential oil, monoterpenes, carotinoids, glycosides, flavanoids, organic acids, lipids, alkaloids and xanthenes 3.
They are used to cure various liver related diseases. Evaluation of hepatoprotective activity of amoora rohituka. Hepatoprotective effect of the solvent extracts of viola. The pdf file you selected should load here if your web browser has a pdf reader plug. Hepatoprotective activity of the ethanolic extract of ficus. Evaluation of hepatoprotective activity of aqeous leaf. International journal of integrative sciences, innovation and technology 20. This work and the related pdf file are licensed under a creative commons. Pdf hepatoprotective activity of some plants extract. The principle depends on the fact that administration of acetaminophen will be associated with development of oxidative stress. Mohammed ishaq 3 deccan school of pharmacy 1, hyderabad, andhra pradesh, india. Hepatoprotective activity of ocimum sanctum alcoholic leaf. Hepatoprotective activity of curcuma xanthorrhiza roxb. This study was undertaken to evaluate the hepatoprotective activity of six commercially.
Hepatoprotective effect of methanolic leave extract of. Hepatoprotective molecules used in emergency medicine edit. Introduction liver is one of the largest organs in human body and the chief site for intense metabolism and excretion. Hepatoprotective effect of polyphenols rich methanolic.
Pdf hepatoprotective activity of six polyherbal formulations in. Evaluation of the hepatoprotective activity of portulaca oleracea l. India is known as a botanical garden of the world because of the largest producer of medicinal plants. These metrics are regularly updated to reflect usage leading up to the last few days. Evaluation of hepatoprotective activity of adansonia digitata. In an attempt to further establish the pharmacological properties of bauhinia purpurea fabaceae, hepatoprotective potential of methanol extract of b. A major project report on evaluation of hepatoprotective activity of amoora rohituka submitted to rajiv gandhi proudyogiki vishwavidyalaya in partial fulfillment of the requirement for degree of master in pharmacy pharmacology, bhopal submitted by shailly malviya supervisor cosupervisor dr.
The purpose of denoising is to remove the noise while. The purpose of this project was to evaluate the hepatoprotective effect of chhitchanthan extract powder cctep. Manokaran s, jaswanth a, sengottuvelu s, nandhakumar j, duraisamy r, karthikeyan d, et al. To study heaptoprotective activity of methanolic extract of whole plant of amaranthus viridis linn meav in paracetamol pcm induced hepatotoxicity. Download this pdf file the pdf file you selected should load here if your web browser has a pdf reader plugin installed for example, a recent version of adobe acrobat reader. This is opposite to hepatotoxicity hepatoprotective molecules used in emergency medicine. Hepatoprotective activity of uncaria tomentosa extract against subchronic exposure to fipronil in male. Hence, we used an animal model with acute alcoholinduced liver injury to evaluate the in vivo antioxidant and hepatoprotective activities of. Hepatoprotective activity of methanol extract of melastoma.
The purpose of this project was to evaluate the hepatoprotective effect of chhit chanthan extract powder cctep. Hepatoprotective activity of the ethanolic extract of. Sgpt, sgot, alp bilirubin and total protein were measured. Download acrobat pdf file 1mb transparency document. Two novel trinorlanostanes, cochlates a and b 1 and 2, with a 3,4seco9,10seco9,19cyclo skeleton, as well as six new triterpenoids, fornicatins df 35 and ganodercochlearins ac 68, together with five known triterpenoids 9, were obtained from the fruiting bodies of ganoderma cochlear. Further studies are in progress to identify the active components responsible for the hepatoprotective and antioxidant activity of a. In vitro and in vivo hepatoprotective activity of cissampelos. Evaluation of hepatoprotective activity of aqeous leaf extract of swietenia.
Evaluation of hepatoprotective and antioxidant activity of. Hepatoprotective activity of talinum portulacifolium forsk. The effects observed were compared with a known hepatoprotective agent, silymarin. On the other hand, seven hemiterpene glycosides were all inactive in. Hepatoprotective activity of exogenous rna the ukrainian. Hepatoprotective activity of ficus carica linn leaf. Hepatoprotective activity of ficus carica linn leaf extract. We have shown that these peptides form second structure characterized by the prevalence of. Hepatoprotective and antioxidant activities of amaranthus viridis linn. Hepatoprotective activity of melia azedarach leaf extract against simvastatin induced hepatotoxicity in rats. Hepatoprotective activity of melia azedarach leaf extract against simvastatin induced hepatotoxicity a. Cibotiumbarosides f and i both exhibited remarkable hepatoprotective activity against apapinduced acute liver damage in vitro, which were more effective than the positive control, bicyclol. If you would like more information about how to print, save, and work with pdfs, highwire press provides a helpful frequently asked questions about pdfs.
Effects of food processing on in vivo antioxidant and. Male albino rats weighing between 150 and 175 g were used as animal models. Evaluation of hepatoprotective activity in paracetamolinduced. Significant hepatoprotective activity of ocimum sanctum was reported earlier against paracetamol, carbon tetrachloride and antitubercular druginduced hepatoxicity in albino rats. Pdf medicinal plants may serve as an essential source of potentially useful new compounds for the development of effective cure to combat a. Hepatoprotective activity of talinum portulacifolium forsk, extract against paracetamol induced hepatic damage in rats. If the inline pdf is not rendering correctly, you can download the pdf file here. Antioxidants free fulltext hepatoprotective effect of. It has a surprising role in the maintenance, performance and regulating homeostasis of the body. The pdf file you selected should load here if your web browser has a pdf reader plugin installed for example, a recent version of adobe acrobat reader if you would like more information about how to print, save, and work with pdfs, highwire press provides a helpful frequently asked questions about pdfs alternatively, you can download the pdf file directly to your computer, from where it.
Hepatoprotective activity of uncaria tomentosa extract against sub. Bacteria associated with the red sea sponge amphimedon ochracea in ccl 4 induced hepatotoxicty in rats abstract fulltext html xml download as pdf. The hepatoprotective activity of these extracts in carbon tetrachloride ccl4, 0. Summary hepatoprotective activity of the nheptane extract of cassia fistula leaves was investigated by inducing hepatotoxicity with paracetamol in rats. Parmar and others published hepatoprotective activity of some plants extract against paracetamol induced hepatotoxicity in wistar rats find, read and cite all the. Hepatoprotective activity of melia azedarach leaf extract. Hepatoprotective activity of centella asiatica linn. Phytochemicals treatments caused a normalized serum aminotransferases activities, decreased level of mda and improved the antioxidant status. Hepatoprotective activity of chitosan nanocarriers loaded with the ethyl acetate extract of a stenotrophomonas sp. Xie wenyan, wang meng, chen chen, zhang xiaoying, melzig matthias f. Hepatoprotective activity of ganoderma lucidum triterpenoids in alcoholinduced liver injury in mice, an itraqbased. Study of hepatoprotective activity of saussurea lappa root. Hepatoprotective activity of sachharum officinarum against paracetamol induced hepatotoxicity in rats. Hepg2 cells showed significant dose dependent increase in percentage viability at the doses 20, 40, 60, 80 and 100 gml of cpre compared to ccl 4 exposed hepg2 cells.
University of khartoum 1993 a thesis submitted in partial fulfillment of the requirements of the university of khartoum for the degree of master in. Evaluation of hepatoprotective activity of adansonia. The methanol extract of the fruit pulp of adansonia digitata l. It is involved with almost all the biochemical pathways to growth, fight against. The liver performs a vital role in metabolism, secretion, storage, and detoxification of endogenous and exogenous substances. Hepatoprotective activity of plectranthus amnoinicus. Hepatoprotective activity of methanolic extract of.
Hepatoprotective activity of methanolic extract of bauhinia. Oxidative stress and free radicals enhance the severity of hepatic damage, which can be overcome by the antioxidant mechanism. Study of the hepatoprotective activity of methanolic extract of feijoa sellowiana fruits against mdma using the isolated rat liver perfusion system. A recent update on hepatoprotective potential of herbal plant mohammad irfan ali1 and manoj kumar2 1school of sciences, suresh gyan vihar university, jaipur302017, rajasthan, india 2marine biotechnology laboratory, department of botany, university of delhi, north campus, india corresponding authoremail. The sixth group standard hepatoprotective received paracetamol followed by naceltylcysteine 100 mgkg orally. The hepatoprotective activity was evaluated by estimating serum alanine aminotransferase, asparatate aminotransferase, alkaline phosphatase, tissue malondialdehyde levels and by histopathological analysis of the liver tissue. Hepatoprotective activity of chhitchanthan extract powder against. Pdf hepatoprotective activity of some plants extract against.
Impact of quantity and frequency patterns on liver disease. The ethanolic extract of ficus carica leaves was screened for hepatoprotective and antioxidant activity in hepatotoxic albino rats induced via carbon tetrachloride. Ten groups of rats n 6 were given a oncedaily administration of 10% dimethyl sulfoxide negative control, 200 mgkg silymarin positive control, or memm 50, 250, or 500 mgkg for 7 days followed by induction of. Hepatoprotective activity of chitosan nanocarriers loaded. Pdf hepatoprotective activity of isolated herbal compounds. Hepatoprotection or antihepatotoxicity is the ability of a chemical substance to prevent damage to the liver. Alternatively, you can download the pdf file directly to your. Leaf extracts were given in the dose of 200 mgkg body weight for 7 days.
Hepatoprotective effect of leaf extracts from citrus hystrix. Coldenia procumbens linn, isoniazid, pyrazinamide, rifampicin, mtt assay. Plant extracts can be the best source of such antioxidants and mediate hepatoprotective activity. The current study investigates phytochemical constituents, antioxidant. A recent update on hepatoprotective potential of herbal plant. The present investigation is aimed to evaluate the hepatoprotective effects of citrus hystrix and citrus maxima red and white variety methanolic leaf extracts on paracetamol induced toxicity. University of khartoum 1993 a thesis submitted in partial fulfillment of the requirements of the university of khartoum for the degree of master in tropical animal health mtah. Hepatoprotective effects of triterpenoids from ganoderma cochlear. The pdf file you selected should load here if your web browser has a pdf reader plugin installed. Hepatoprotective and antioxidant activities of amaranthus. It is a seminar on hepatoprotective drug authorstream presentation.
They are mainly caused by uses of high doses of chemicals and some drugs. Hepatoprotective agents dr priyank shah, jr 1, dept of pharmacology 1 2. View of phytochemical screening and evaluation of hepatoprotective. Phytochemistry and hepatoprotective activity of aqueous. Malvaceae was examined for its hepatoprotective activity against liver damage induced by acetaminophen in rats. The present study aimed to determine the hepatoprotective activity of a methanol extract of melastoma malabathricum leaves memm using two established rat models. Hepatoprotective effect of leaf extracts from citrus. To download the pdf, click the download link above. Peptides molecular weights are 1200 11,600 da biologically acting at concentration 108 1015 mgml were obtained from leaves of dill anethum graveolens l. Green tulsi ocimum sanctum, belonging to family lamiaceae are used traditionally for their hepatoprotective effect. The present study investigated the protective effects of moringa oleifera leaves extract.
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